Tanzania

Public Health Laboratory Ivo de Carneri

Expertise

The Public Health Laboratory - Ivo de Carneri (PHL-IdC) has vast experience in planning and executing field activities related to parasitic diseases, particularly neglected tropical diseases (NTDs). PHL-IdC covers a variety of research areas ranging from the evaluation of diagnostic tools to detect helminth eggs to the assessment of both the drug efficacy and safety. Due to its expertise,  the Public Health Laboratory is a World Health Organization Collaborating Center for NTDs.

Role in the project

PHL-IdC is one of the three World Health Organization Collaborating Centeres that were involved in the development of the project and acts as co-principal investigator. It contributes to the design and the monitoring of the proposed field trials. In addition, it performs the different activities out lined in work package 1 and it provides technical support in the countries involved in work package 2.

Team members

Upper row: Dadi Kombo Dadi, Mohammed Farouk, Ali Hamad, Piet Cools (Ghent University, Belgium), Yahya Muhammed, Hemed Mbarouk, X. Middle row: Nuwaira Ali, Hali Sheha Halima, Asila Abdulrahman, Thuwayba, Khamis Rashid Suleiman, Bimkubwa, Nayha Haroub, Ahmed Haji, Lower row: Kheir Bakari, Ghanil Moh'd Khatib, Mio Ayana Heda  (Jimma University, Ethiopia), Issa Khamis, Shaali Ame. 

Main publications linked to the project

• Speich B et al., 2016. Efficacy and reinfection with soil-transmitted helminths 18-weeks post-treatment with albendazole-ivermectin, albendazole-mebendazole, albendazole-oxantel pamoate and mebendazole. Parasit Vectors 2:123
• Moser W et al., 2016. Efficacy and safety of oxantel pamoate in school-aged children infected with Trichuris trichiura on Pemba Island, Tanzania: a parallel, randomised, controlled, dose-ranging study. Lancet Infect Dis 16:53-60.
• Speich B et al., 2015. Efficacy and safety of albendazole plus ivermectin, albendazole plus mebendazole, albendazole plus oxantel pamoate, and mebendazole alone against Trichuris trichiura and concomitant soil-transmitted helminth infections: a four-arm, randomised controlled trial. Lancet Infect Dis 15:277-284

• Levecke B et al., 2014. Assessment of anthelmintic efficacy of mebendazole in school children in six countries where soil-transmitted helminths are endemic. PLoS Negl Trop Dis 8: e3204.

• Albonico A et al., 2013. Comparison of three copromicroscopic methods to assess albendazole efficacy against soil-transmitted helminth infections in school-aged children on Pemba Island. Trans R Soc Trop Med Hyg 107:493-501.

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